According to Article 14, Paragraph 1 of this law, manufacturers, importers, suppliers, or employers shall not manufacture, import, supply, or allow workers to handle or use controlled chemical substances designated by the central competent authority. However, those permitted by the central competent authority are not subject to this restriction. In accordance with the authorization provisions of Paragraph 3 of the same article, the central competent authority shall determine the methods for the designation of controlled chemical substances, conditions for permits, duration, abolition or withdrawal of permits, content of operational data, and other matters to be followed. Therefore, the "Regulations for the Designation and Operational Permits of Controlled Chemical Substances" are proposed.